Ethics approval and patient consent are not required as this study is a systematic review based on published articles INPLASY202050079 INPLASY202050079 Academic self-concept is an important construct within the disciplines of medicine, psychology, and education Enhancing the academic self-concept of students with special educational needs is very crucial because it is associated with their quality of life This study aimed to examine the effect of a video-guided educational technology intervention on the academic self-concept of adolescents with hearing impairment who were attending inclusive nonresidential public schools in Southeast Nigeria This study adopted a randomized controlled trial design The participants were 60 junior secondary students with hearing impairment We implemented a video-guided educational technology intervention It relied on the use of 13-minute video clips with captions/subtitles, which covered academic self-concept-related themes The Academic Self-Concept Questionnaire, which has been developed by Liu and Wang, was used to collect baseline, posttreatment, and follow-up data We conducted independent-samples and paired t tering impairments who attend inclusive non residential public schools in Nigeria The video-guided educational technology intervention was effective in improving the academic self-concept of adolescents with hearing impairment who were attending inclusive nonresidential public schools Large-scale studies are needed to maximize the impact of video-guided educational technology interventions on students with hearing impairments who attend inclusive non residential public schools in Nigeria Delirium is a frequently encountered complication, which is associated with increased mortality Suvorexant, an approved agent for the treatment of insomnia, is recently suggested to be also effective for prevention of delirium by some authors However, a consensus has yet to be reached The goal of this study was to perform a meta-analysis to overall estimate the effectiveness of suvorexant in preventing delirium and its related consequences Eligible studies were identified by searching online databases of PubMed, EMBASE, and Cochrane Library The pooled OR was calculated for binary outcomes eg, the incidence of delirium, mortality, or adverse events, while standardized mean difference SMD were expressed for continuous outcomes eg, time to delirium onset, length of stay in hospital and ICU, time on ventilation Seven studies which comprised 402 suvorexant treatment patients and 487 patients with control treatment were included in this meta-analysis Overall, pooled analysis indicated the incidence of delirium could be significantly reduced OR, 030; P lt; 001 and time to delirium onset was significantly lengthened SMD, 044; P = 006 in patients undergoing suvorexant treatment compared with controls Suvorexant had no beneficial effects on the secondary outcomes [length of stay in hospital SMD, -065; P = 161 and ICU SMD, 034; P = 297, time on ventilation SMD, 109; P = 318, drug-related adverse events OR, drug-related adverse events OR, 166; P = 319 and mortality OR, 221; P = 261] https//wwwselleckchemcom/products/Eloxatinhtml Subgroup analysis also confirmed the benefit of suvorexant on the development of delirium, which was significant in any subgroup Suvorexant should be recommended for the prevention of delirium in clinic Suvorexant should be recommended for the prevention of delirium in clinic Since the outbreak of Novel Coronavirus Pneumonia NCP, it has swept the world with rapid development Up to now, there is no effective drug to treat it Lianhua Qingwen has been used in the treatment of COVID-19 in China, but there is no systematic review about it This study will systematically evaluate its efficacy and safety in the treatment of COVID-19 We will search electronic database of PubMed, EMBASE, Cochrane library, Web of Science WOS, China National Knowledge Infrastructure CNKI, Chinese Biomedical Literature Database CBM, Chinese Scientific and Journal Database VIP and Wan Fang database Wanfang for the literature of RCTs of Lianhua Qingwen capsule for coronavirus disease 2019 COVID-19 We will also search the Chinese Clinical Trial Registry ChiCTR and ClinicalTrialsgov wwwClinicalTrialsgov for ongoing trials with unpublished data, and the Conference abstracts will be searched manually We will use the Cochrane Handbook for Systematic Reviews of Interventions to assess the risk of bias The protocol will be conducted according to the approach and Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols PRISMA-P The study results will provide evidence of the efficacy and safety of Lianhua Qingwen LHQW for coronavirus disease 2019 COVID-19 The result of the study will be published in a peer-reviewed journal CRD42020180877 CRD42020180877 To compare clinical effect between Er YAG and CO2 laser in treatment of oral tumorous lesions A comprehensive search was conducted from 2000 to 2019 The quality assessment was performed by the QUADAS-2 tool The Cochrane Collaboration, 2011 The clinical value of comparison between Er YAG and CO2 laser was evaluated by using the pooled estimate of sensitivity and specificity In addition, sensitivity analysis and bias analysis were applied to ensure the accuracy of the results Finally, 268 patients were enrolled in 6 studies and ultimately met the eligibility criteria The Er YAG and CO2 groups were 141 and 127, respectively The meta-analysis showed significant difference in success risk ratio  = 2129, 95 confidence interval [109, 152], P = 002; P for Heterogeneity = 99, I = 0 and time of surgery P of heterogeneity = 29, I = 20, Z = 2569, P of over effect lt; 00001 The recurrence and complications of CO2and Er YAG groups had no difference Er YAG laser had better effects than CO2 laser in eliminating oral tumorous lesions while it needed longer operation time than CO2 laser Er YAG laser had better effects than CO2 laser in eliminating oral tumorous lesions while it needed longer operation time than CO2 laser