While all of the vaccines elicited similar OspA antibody responses, only Subunit-AC triggered a robust and broadly cross-reactive antibody response to divergent OspC proteins The data presented within provide new information regarding vaccination-induced antibody responses to key tick and mammalian phase antigens by both subunit and bacterin LD canine vaccine formulationsThe peripartum period is critical in equine medicine for maintaining healthy mares, and ensuring the delivery of healthy neonatal foals The field of perinatal mortality in horses is continuously evolving, with several advances being recently made in causes of perinatal fetal and foal loss This review details the main causes of perinatal loss in horses, through late pregnancy, parturition and the neonatal period Recent advances in identification of infectious organisms and indicators of survival in neonatal foals will be discussed Continued advances in reproductive and neonatal medicine will aid improved survival of foals through fewer pregnancy losses, and improved management of high-risk pregnancies and critically ill neonatal foalsIn the United States, economic, racial, ethnic, geographic, and other disparities prevent access to fertility treatment and affect treatment outcomes This opinion examines the factors that contribute to these disparities, proposes actions to address them, and replaces the document of the same name, last published in 2015Programs should create and enforce written policies addressing the designation, retention, and disposal of unclaimed embryos In the absence of program-specific policies, it is ethically permissible for a program or facility to consider embryos to have been unclaimed if a reasonable period of time has passed since contact with an individual or couple; efforts as outlined in the consent form have been made to contact the individual or couple; and no written instructions from the individual or couple with dispositional control exist concerning disposition In such cases, programs or facilities may dispose of unclaimed embryos by removing them from storage and thawing without transfer In the absence of specific written instructions, unclaimed embryos may not be donated to others for reproductive use or be used in research This statement replaces the American Society for Reproductive Medicine Ethics Committee document "Disposition of Abandoned Embryos" published in 2013The aim of this article is to gather 9 thought leaders and their team members to present their ideas about the future of in vitro fertilization and the andrology laboratory Although we have seen much progress and innovation in the laboratory over the years, there is still much to come, and this article looks at what these leaders think will be important in the future development of technology and processes in the laboratory To provide evidence-based recommendations to practicing physicians and others regarding the efficacy of oocyte cryopreservation OC for donor oocyte invitro fertilization and planned OC The American Society for Reproductive Medicine conducted a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 1986 to 2018 The American Society for Reproductive Medicine Practice Committee and a task force of experts used available evidence and through consensus developed evidence-based guideline recommendations Outcomes of interest included live birth rate, clinical pregnancy rate, obstetrical and neonatal outcomes, and factors predicting reproductive outcomes The literature search identified 30 relevant studies to inform the evidence base for this guideline Evidence-based recommendations were developed for predicting the likelihood of live births after planned OC, autologous OC in OC at a younger vs older age Although there are no significant differences in per transfer pregnancy rates with cryopreserved vs fresh donor oocytes, there is insufficient evidence that the live birth rate is the same with vitrified vs fresh donor oocytes Neonatal outcomes appear similar with cryopreserved oocytes compared with fresh oocytes Future studies that compare cumulative live birth rates are neededThe in vitro fertilization and andrology laboratories are at the center of assisted reproductive technologies and the place where technicians and embryologists manipulate gametes and preimplantation-stage embryos with the goal of achieving the best embryo for transfer Through the years, these laboratories have seen developments in technique, technology, and testing The goal of this Views and Interviews series is to bring together the thought leaders in the field and envision what the laboratories will look like in the next 10 years To evaluate the evidence addressing the association between the use of ovarian stimulation drugs and the risk of breast cancer Systematic review and meta-analysis Not applicable Women without any previous history of breast cancer undergoing ovarian stimulation Electronic databases were searched from 1990 until January 2020 All cohort studies reporting new incidences of breast cancer in infertile women using ovarian stimulating drugs were included Treated exposed infertile women were compared with the unexposed general population with unexposed infertile women as controls New diagnosis of breast cancer within an infertile and general population after exposure to ovarian stimulation drugs Overall, the quality of evidence was very low because of the serious risk of bias and indirectness nonrandomized studies There was no significant increase in the risk of breast cancer among women treated with any ovarian stimulation drug for infertility compared with that in unexposed controls from the general population and the infertile population pooled odds ratio 103, 95 Confidence interval 086 to 123, 20 studies, I = 8841, very low quality of evidence https//wwwselleckchemcom/products/apr-246-prima-1methtml Furthermore, no significant increase in the risk of breast cancer was found with the use of clomiphene citrate or gonadotropins, alone or in combination The current study found that the use of clomiphene citrate and gonadotropins in infertile women was not associated with an increased risk of breast cancer The current study found that the use of clomiphene citrate and gonadotropins in infertile women was not associated with an increased risk of breast cancer