<p>RESULTS The booklet presented a global Content Validity Index of 0.92. The overall level of agreement within the target participants was 86.3%, which was higher than the minimum recommended level. Both subject experts and participants positively evaluated the adequacy, coverage and readability of contents of the booklet. CONCLUSIONS The booklet was validated using content and face validity. This validated booklet is expected to be an effective tool for communication that would help pregnant women cope better with domestic and family violence and adopt strategies to remain emotionally healthy.BACKGROUND Repetitive exposure to vibration has been shown to induce peripheral nerve dysfunction. Dentists are exposed to handheld vibrating tools in their daily clinical practice. Most of the studies are done in dentists who have symptoms such as paresthesia and numbness of the hands. Thus, we conducted the study to explore the effect of vibration on nerve conduction variables in apparently healthy asymptomatic dental residents. METHODS This cross-sectional study enrolled 22 dental residents and age matched 22 medical residents as controls.  <a href="https://www.selleckchem.com/products/selonsertib-gs-4997.html">Selonsertib chemical structure</a> Nerve conduction study was performed in median and ulnar nerves of both hands. RESULTS Anthropometric and cardiorespiratory variables were comparable between the groups. There were no statistically significant differences between dental and medical residents in the sensory conduction variables (right median onset latency=2.05±0.27 vs 1.91±0.21, p value=0.07; right median amplitude =27.80±8.11 vs 29.55±7.04, p=0.45; right median conduction velocity = 59.54±7.05 vs 61.06±5.15, p= 0.42) and motor conduction variables (right median distal latency = 2.87±0.38 vs 2.87±0.38, p= 0.94; right median distal amplitude=10.71±2.19 vs 11.10±2.37, p=0.58; right median conduction velocity= 70.57±13.16 vs 68.53±7.73, p= 0.54) of median and ulnar nerves. Further, there was no significant difference between the dominant and non-dominant hands of dental residents. CONCLUSIONS Hand held vibration tools did not alter nerve conduction study parameters of dental residents.BACKGROUND Low birth weight is a factor associated with perinatal, neonatal and post-neonatal morbidity and mortality and is associated with development of chronic diseases in adulthood. This study aimed to identify the maternal and obstetric factors associated with low birth weight in selected hospitals of Nepal. METHODS Matched case control study was conducted in two tertiary level hospital of Nepal during May 2017 to April 2018. There were 368 mothers with single full term live low birth weight babies (cases) and 736 mothers with single full term live normal birth weight babies (controls) matched on babies' gender and place of delivery included in the study. Multivariable conditional logistic regression analysis was used to eliminate the effects of potential confounders and to identify the independent effect of various risk factors associated with low birth weight. RESULTS A total of 1104 respondents (1 case  2 controls) were included in the study. Multivariable conditional logistic regression analysis revealed that maternal height  less then 146 cm [AOR 5.14, (95%CI2.03-13.01),(p=0.001)], maternal weight ?50 kg [AOR 3.75,(95%CI2.15-6.56), (p less then 0.001)], primi-parity [AOR 4.58, (95%CI1.71-12.25),(p=0.002)], multi-parity [AOR 3.01,(95%CI 1.11-8.12),(p=0.030)], rest in day time ?2 hours [AOR 3.68, (95%CI 2.01-6.75),(p less then 0.001)], rest in night time for  less then 8 hours [AOR 5.76, (95%CI 2.32-14.33), (p less then 0.001)], Iron and folic acid consumption for ?60 days [AOR 5.47, (95%CI 2.73-10.95),(p less then 0.001)], Iron and folic acid consumption for 61-120 days [AOR 3.04, (95%CI 1.90-4.87),(p less then 0.001), no calcium consumption [AOR 3.00, (95%CI 1.78-5.04),(p less then 0.001)] were the significant risk factors associated with Low birth weight Conclusions Height and weight of women, parity, duration of rest in day time and night time, consumption of Iron and folic acid and calcium were the maternal and obstetric determinants for the occurrence of low birth weight.BACKGROUND Adolescence is a critical period and is associated with physical and psycho-social changes induced by puberty, which builds personality, behaviour, and future health of the adolescents. Thus, the aim of the study was to find out the knowledge and attitude regarding pubertal health of adolescence girls. METHODS A descriptive cross sectional study was conducted in Bharatpur Metropolitan City's secondary level schools. A total of 183 adolescent girls were selected using probability simple random sampling from 5 schools out of total 43 schools which were also selected by simple random sampling technique. Data was collected by using structured self-administered questionnaire for knowledge and likert's scale was used for attitude regarding pubertal health. RESULTS Study findings revealed that 61.4% of the students belonged to early adolescence (11-14) age group with the mean age 14.27±1.33 years. Majority (80.3%) had moderate level of knowledge and around half (48.6%) had positive attitude. Knowledge and attitude varied with the respondents' level of education (p=0.001), relation to sibling (p=0.013) and source of information by elder sister (p=0.022), teachers/school (p=0.001).Moderately positive correlation was found between knowledge and attitude which was highly significant (r=0.395, p less then 0.001). CONCLUSIONS Majority of respondents had moderate level of knowledge and half of the respondent had positive attitude regarding pubertal health. Findings of the study emphasizes on improvement in education of adolescent girls which can help uplift health status and minimize vulnerability to health issues of pubertal health.BACKGROUND Newborn service readiness is facility's observed capacity to provide newborn services and a pre-requisite for quality. Newborn services are priority program of government and efforts are focused on infrastructure and supplies at peripheral health facilities. Study describes health facility readiness for newborn services in four domains of general requirements, equipment, medicines and commodities, and staffing and guidelines. METHODS Convergent parallel mixed method using concurrent triangulation was done in public health facilities providing institutional deliveries of two randomly selected districts- Taplejung and Solukhumbu of Eastern Mountain Region of Nepal. Face to face interview and observation of facilities were done using structured questionnaire and checklist; in-depth interviews were done using interview guideline from November 2016 to January 2017. Ethical clearance was taken. Descriptive analysis and deductive thematic analysis were done. RESULTS Mean score of newborn service readiness was 68.</p>