The exploration of emergency materials with ultra-fast adsorption rate and great adsorption capability of released UVI ions is essentially urgent The present work successfully fabricated bundle-like hydroxyapatite B-HAP microstructures which composed of numerous nanorods by employing a facile and green method The B-HAP was applied to treat the UVI containing wastewater The abatement of UVI by B-HAP was very rapid and the saturated adsorption capacity was superior; over 967  of UVI was abated within 5 min, and the maximum adsorption capacity was as high as to 1305 mg/g, signifying the feasibility and effectiveness of this B-HAP in the treatment of uranium-contaminated wastewater due to nuclear accidents It is worthy to note that other ions in solution exhibited relatively low interference on its performance, indicating that B-HAP has great application potential to capture UVI from radioactive-contaminated wastewater as well The UVI removal mechanism by B-HAP was confirmed with results from XRD, FT-IR and XPS Chernikovite [H2UO22PO42·8H2O] was newly formed after UVI abatement by B-HAP Economic assessment suggested B-HAP and its application on UVI abatement were cost-effective With characteristics of high adsorption rate, large capacity, and strong antijamming ability, B-HAP has great application potential as an emergency treatment material for nuclear accidents In this work, we report the synthesis of two receptors for fluoride ions based on acyl hydrazone, such as N'-[1Z-1-4-fluorophenylethylidene]benzohydrazide R1 and N'-[1Z-1-2-hydroxyphenylethylidene]benzohydrazide R2 The receptors R1 and R2 were synthesized from the corresponding ketones and benzoic acid hydrazide and characterized spectroscopically by UV-visible, IR and 1HNMR techniques The response of R1 and R2 towards different anions was studied colourimetrically in acetonitrile The receptors exhibited a specific response towards fluoride ions Further studies of 11 composition of receptors, R1/R2fluoride ions by different spectroscopic techniques such as UV-Visible, IR and 1HNMR spectroscopy indicated the participation of -NH proton of the receptors in the sensing action through the hydrogen bonding To understand the mechanism, Time-Dependent Density Functional Theory TD-DFT studies were done using the CAM-B3LYP/6311G++ 3df,2p with Grimme's D3BJ empirical dispersion basis set The studies supported the role of hydrogen bonding interaction of -NH and-OH protons of the receptors with the fluoride ions By modifying 4'‑hydroxybiphenyl‑4‑carbonitrile BPN-OH with 2‑4‑bromo‑methylphenyl‑4,4,5,5‑tetramethyl‑1,3,2‑dioxaborolane group, a facile fluorescent probe, BPN-TOB, for sensitively tracing H2O2 was designed and synthesized BPN-TOB displayed a low detection limit 67nbsp;nM, fast response time 10nbsp;min, low cytotoxicity, a mega Stokes shift 170nbsp;nm and a remarkable fluorescence enhancement 72-fold in the detection of H2O2 Additionally, probe BPN-TOB could monitor exogenous and endogenous H2O2 in living MGC-803 cells human gastric cancer cells and RAW2647 cells leukemia cellsin mouse macrophage In particular, this probe BPN-TOB was successfully utilized for imaging H2O2 in zebrafish Fluorescence properties of nanoparticles can be influenced by solvent In this work, carbon dots CDs were synthesized in deep eutectic solvent by microwave assisted method Quantum yield QY and size of the synthesized CDs were 413 and 2nbsp;nm, respectively N/Cl -doped CDs had excellent sensitivity and selectivity for atorvastatin and detection limit was 08nbsp;nM Simple and low-cost synthesis method and excellent sensitivity are advantages of this detection method for atorvastatin The as-synthesized N/Cl-doped CDs were successfully used to determine atorvastatin in blood serum VTwo asymptotic constant ratio methods applied to the quantification of individual components of solid samples using attenuated total reflectance-Fourier transform infrared spectroscopy ATR-FTIR and X-ray diffraction XRD are described The methods involve the measurement of the peak current/peak areas of selected signals diffraction peaks in XRD and absorption bands in ATR-FTIR relative to the signal of standard added in constant proportion to the sample and the sample enriched with the analyte following the usual standard additions methodology The proposed method compensates the absorption effects appearing in XRD and the presence of overlapping absorption bands of interferents by means of an asymptotic representation thus avoiding the need of the knowledge of the absorption parameters of the matrix and analytes The method was tested for mixtures of different metal oxides and sodium and potassium feldspars with satisfactory results BACKGROUND Extensive research on the link between the organizational characteristics of the work environment and patient safety in a healthcare organization has been conducted; yet, only a few studies have concentrated on care providers in a pediatric unit OBJECTIVES To determine the correlation between different work environment factors impacting patient safety in a pediatric care unit from the perspective of registered nurses working in these units DESIGN Cross-sectional design DATA SOURCES AND METHODS The study was conducted with 155 registered nurses from a pediatric unit in a medical center in Taiwan with the Chinese version of the Safety Attitudes Questionnaire SAQ 2014-2017 RESULTS Teamwork climate, higher job satisfaction, and better working conditions are linked to positive perceptions of patient safety culture Emotional exhaustion is negatively related to most dimensions of patient safety CONCLUSION Teamwork climate, job satisfaction, working conditions, and emotional exhaustion were identified as critical factors impacting the patient safety climate IMPLICATIONS FOR NURSING OR HEALTH POLICY Investments to improve teamwork climate, job satisfaction, and working conditions and reduce emotional exhaustion may have a positive effect on patient safety in pediatric care units As one of the most popular non-linear models, artificial neural network ANN has been successfully applied in the prediction of municipal solid waste MSW Despite its high accuracy achieved in a specific city or region, little progress is made on a larger-scale, which would be resulted from the regional difference In this study, ANN models for MSW prediction in mainland China are developed and optimized Besides a model aiming for all cities, regional models are developed by grouping these cities into three categories Impact of regional difference in MSW prediction is analyzed by evaluation of model's dependence on each predictor, and comparisons made between these models Results show that regional difference has huge impact on MSW prediction Accuracy of MSW prediction would increase from 0916 in R2 and 593 in rooted mean squared error RMSE to 0968/0946/0943 in R2 and 64/97/176 in RMSE for southern/northern/western region after a three-region division Models for MSW prediction in southern and northern region of mainland China share much similarity in dependence on predictors, which differs a lot from that for western region Further cross-prediction process confirmed that models for southern or northern regions might be suitable for the MSW prediction in another, yet not apply to that in western region Such large-scale based model can be used by cities lacking historical data for prediction of their local MSW generation, the predictive result would be helpful in MSW disposal planning and the analysis of regional difference would be helpful in establishing regional policy, especially for the three regions in mainland China Yarrowia lipolytica has emerged as an important non-model host for terpene production However, three main challenges remain in industrial production using this yeast First, considerable knowledge gaps exist in metabolic flux across multiple compartments, cofactor generation, and catabolism of non-sugar carbon sources Second, many enzymatic steps in the complex-terpene synthesis pathway can pose rate-limitations, causing accumulation of toxic intermediates and increased metabolic burdens Third, metabolic shifts, morphological changes, and genetic mutations are poorly characterized under industrial fermentation conditions To overcome these challenges, systems metabolic analysis, protein engineering, novel pathway engineering, model-guided strain design, and fermentation optimization have been attempted with some successes Further developments that address these challenges are needed to advance the Yarrowia lipolytica platform for industrial-scale production of high-value terpenes, including those with highly complex structures such as anticancer molecules withanolides and insecticidal limonoids Cardiovascular abnormalities are one of the most important complications associated with diabetes However, the effect of 1, 25-dihydroxyvitamin D 1,25D on the diabetic heart and the associated regulatory mechanisms are not well appreciated Here, we report that activation of the vitamin D receptor VDR by 1,25D depresses autophagic activity by inhibiting nuclear FoxO1 translocation to attenuate diabetic heart damage Treatment with 1,25D improved oral glucose tolerance test outcomes, fasting blood glucose levels and CK-MB release in Zucker diabetic fatty ZDF, fa/fa rats Moreover, 1,25D intervention decreased the expression of Bcl-2, Bax, cleaved caspase-3, nuclear FoxO1, LC3II/LC3I and Beclin1 in the hearts of ZDF rats However, VDR was noticeably up-regulated by 1,25D, which was inhibited in diabetic hearts In the cardiomyocyte cell line H9c2, further accumulation of LC3II and the augmentation of p62 after treatment with high glucose and chloroquine confirmed increased autophagic activity in diabetic hearts Moreover, increased Bcl-2 and Bax levels were observed after treatment with an agonist rapamycin and antagonist 3MA of autophagy in high-glucose-cultured cells The knockdown of VDR with siRNA further induced the expression of LC3II and FoxO1 translocation and altered the Bax/Bcl-2 ratio in high-glucose-exposed cells, and these effects were suppressed by treatment with 1,25D or an inhibitor of FoxO1 transcriptional activity In summary, 1,25D supplementation attenuated diabetic heart-related cardiac autophagy and damage by activating the VDR to inhibit the nuclear translocation of FoxO1 Dichlorodiphenyl trichloroethane DDT is an organochlorine insecticide that is banned internationally except for use as part of Indoor Residual Spraying IRS programs to control malaria  https//wwwselleckchemcom/products/bay-876html  Although animal studies show that DDT and its breakdown product dichlorodiphenyl dichloroethylene DDE affect the immune system and may cause allergies, no studies have examined this question in populations where IRS is conducted The aim of our study was to investigate whether prenatal exposure to DDT and DDE is associated with allergy symptoms and diagnose among South African children living in an area where IRS is conducted To accomplish this aim, we used data from the Venda Health Examination of Mothers, Babies and their Environment VHEMBE, an ongoing birth cohort study of 752 children born between 2012 and 2013 in the rural Vhembe district of Limpopo, South Africa We measured maternal peripartum serum concentrations of DDT and DDE, and administered a questionnaire to the caregivers of 658 children aged 35 years to collect information on allergy symptoms and diagnoses as well as potential confounders using validated instruments