In addition, we provide information on the patch size, connectivity, and urban intensity, using four remote sensing-based proxies measured at 100- and 800-m radii[This corrects the article DOI 101016/jdib2021106931]Growing evidence demonstrates the epigenetic modulation as a key event in Alzheimer's disease AD pathology Furthermore, recent data suggests that the epigenetic regulation by the methyltransferase G9a is a crucial mechanism involved in learning and memory formation Taking this into account, we hereby provide genomics data from pharmacological intervention with UNC0642, a potent and selective G9a/GLP in SAMP8 mice, a model of Alzheimer's disease AD We have generated novel RNA-seq and miRNA-seq data for three groups, healthy SAMR1, SAMP8 control and SAMP8 treated with UNC0642 5 mg/Kg Thus, the new data can be used to find miRNA regulation, and the mRNA's modified in AD under G9a/GLP inhibitionThe article is aimed at assessing the effects of chronic exposure to non-combusted LPG on the prevalence of respiratory symptoms and appraising the potential pulmonary impairments among LPG vendors A case control design in which vendors and non-vendors of LPG from Calabar, Nigeria were used for the data collection Seventy five 75 apparently healthy LPG vendors and Seventy five 75 apparently healthy non LPG vendors, aged 18 to 50 years were considered A structured questionnaire was randomly administered to the participants to obtain information on age, family history, medical history, physical lifestyle, drug usage, occupation and duration on the job The Forced expiratory volume in 1 second FEV1, forced vital capacity FVC and peak expiratory flow PEF were obtained using a Spirometer while FEV1/FVC was calculated Independent t-test was applied to determine the mean difference between the exposed and control groups at 5 level of significance Chi-square test/Fisher's exact test was used to investigate all forms of associations in the study It is evident in the data that nasal irritation/sneezing and cough were significantly associated with the LPG vendors The pulmonary function parameters except FEV1/FVC indicated significant reduction among LPG vendors The data can further be reused by applying regression analysis, correlation analysis to determine the relationship between pulmonary function indices and duration of exposure Also, analysis of variance ANOVA can be used for determining the effect of interaction between age of exposed group and duration of exposure on pulmonary function parametersThe data presented in this article pertain to field records of EPB shield machine in Metro Line No 5 in Tianjin, China Field performance of shield machine cutterhead, screw machine, and shield advancing are shown in the figures Specifically, the database consists of the main parameters for shield tunnelling including cutterhead rotation speed, cutterhead torque, screw machine rotation speed, screw machine torque, shield thrust, and shield advance rate In addition, the calculation process of energy consumption and variation index R2 during the tunnelling are displayed The value of the dataset is the consideration of silt or clay soil encountered in the shield tunnelling area including the proportion of soils, grain gradation, and effects on performance and energy consumption of different parts in shield machine These field data are applied to evaluate the construction efficiency in the article titled "Construction efficiency of shield tunnelling through soft deposit in Tianjin" [1]The dataset herein indicated the novelty of the article entitled "Dataset on the use of MGIDI in screening drought-tolerant wild wheat accessions at the early growth stage" Data were gathered during 2018-2019 on a set of wild wheat germplasm under two control and water deficit stress conditions One hundred and forty-six accessions belonging to Ae tauschii, Ae cylindrica, and Ae crassa were assessed under optimal glasshouse conditions to screen the drought-tolerant samples at the early growth stage Nine drought tolerance and susceptibility indices along with the multi-trait genotype-ideotype distance index MGIDI were used to visualize the dataset The obtained data can highlight the potential of the MGIDI index in accelerating screening of a large number of plant materials using multiple traits or selection indices in crop breeding programs, especially at the early growth stageThis article presents a database containing 757 color fundus images acquired at the Department of Ophthalmology of the Hospital de Clínicas, Facultad de Ciencias Médicas FCM, Universidad Nacional de Asunción UNA, Paraguay Firstly, the retinal images were acquired with a clinical procedure presented in this paper  https//wwwselleckchemcom/products/noradrenaline-bitartrate-monohydrate-levophedhtml  The acquisition of the retinographies was made through the Visucam 500 camera of the Zeiss brand Next, two expert ophthalmologists have classified the dataset These data can help physicians and researchers in the detection of cases of Non-Proliferative Diabetic Retinopathy NPDR and Proliferative Diabetic Retinopathy PDR, in their different stages The dataset generated will be useful for ophthalmologists and researchers to work on automatic detection algorithms for Diabetic Retinopathy DRShiga toxin-producing Escherichia coli STEC strain RM13514 is a clinical isolate linked to the 2010 romaine lettuce-associated outbreak in the US The genes encoding a type II restriction and modification system, PstI R-M, are located in a prophage genome that is also encoding Shiga toxin In-frame deletion of the PstI R-M genes or dam, encoding a DNA adenine methylase, in strain RM13514 were generated, resulting in two mutant strains MQC599 and MQC602, respectively The mutant strain MQC599 exhibited a similar growth rate as the wild-type WT strain RM13514 when grown in Luria-Bertani LB broth at 37 °C In contrast, the growth of mutant strain MQC602 was significantly slower than either RM13514 or MQC599 Genes transcriptionally regulated by the PstI R-M system or by Dam were examined by the RNA-Seq based comparative transcriptomics The total RNA was extracted from cells of each strain grown in LB broth at exponential and stationary phases Three biological replicates were collected for each strain Aarchers who are interested in physiology and pathogenicity of foodborne pathogens or in the fundamental mechanisms of epigenetic regulation in bacteriaHourly heat flux for variant boundary conditions of a novel controlled-temperature double skin façade DSF building element in a two- dimensional time- dependent study was determined The building element is subjected to boundary conditions, characterizing different orientations azimuth 0°, 90°, 180°, 270° and climatic conditions of the four seasons This data article provides detailed numerical data on the hourly heat flux, temperatures attained at the exterior and within the building element for six different geometries and for the variant boundary conditions under study The external boundary conditions were determined with the use of the PVGIS tool, corrected in accordance to the sol-air temperature equation The numerical simulation studies were performed with the use of the computational fluid dynamics CFD tool Comsol Multiphysics [2]Information on the biodistribution BD of cell therapy products CTPs is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods This review aimed at surveying international and Japanese trends concerning the BD study for CTPs and the following subjects were investigated, which were considered particularly important 1 comparison of guidelines to understand the regulatory status of BD studies in a global setting; 2 case studies of the BD study using databases to understand its current status in cell therapy; 3 case studies on quantitative polymerase chain reaction qPCR used primarily in non-clinical BD studies for CTPs; and 4 survey of imaging methods used for non-clinical and clinical BD studies The results in this review will be a useful resource for implementing BD studies
  The skin is comprised of various kinds of cells and has three layers, the epidermis, dermis and subcutaneous adipose tissue Stem cells in each tissue duplicate themselves and differentiate to supply new cells that function in the tissue, and thereby maintain the tissue homeostasis In contrast, senescent cells accumulate with age and secrete senescence-associated secretory phenotype SASP factors that impair surrounding cells and tissues, which lowers the capacity to maintain homeostasis in each tissue Previously, we found Gremlin 2 GREM2 as a novel SASP factor in the skin and reported that GREM2 suppressed the differentiation of adipose-derived stromal/stem cells In the present study, we investigated the effects of GREM2 on stem cells in the epidermis and dermis
 
  To examine whether GREM2 expression and the differentiation levels in the epidermis and dermis are correlated, the expressions of GREM2, stem cell markers, an epidermal differentiation marker Keratin 10 KRT10 and a dermal differentiation epidermal and dermal stem/progenitor cells
  Idiopathic dilated cardiomyopathy DCM is associated with abnormalities in cytoskeletal proteins, mitochondrial ATP transporter, microvasculature, and fibrosis Mesenchymal stem cells MSCs can ameliorate distressed mitochondrial and structural proteins, as well as fibrosis, via the paracrine effect of cytokines This study aimed to investigate whether the transplantation of adipose tissue-derived MSCs ADSCs reverses histological and functional abnormalities in the distressed myocardium of DCM-like hamsters by modulating the expression of adenine nucleotide translocase 1 ANT-1
 
  Eighteen weeks after birth, ADSCs were implanted onto the cardiac surface of δ-sarcoglycan SG-deficient hamsters or sham surgery was performed
 
  Left ventricular ejection fraction and end-systolic diameter were maintained in ADSC-treated animals for four weeks, ATP concentration was considerably elevated in the cardiomyocytes of these animals, and ANT-1 expression was significantly upregulated as well The expression of extracellular matrix and myocardial cytoskeletal proteins, such as collagen, SG, and α-dystroglycan, did not differ between groups However, significant improvements in myosin and Smad4 expression, cardiomyocyte hypertrophy, and capillary density occurred in the ADSC-treated group
 
  We demonstrated that ADSCs might maintain cardiac function in the DCM hamster model by enhancing ATP concentration, as well as mitochondrial transporter and myosin expression, indicating their potential for DCM treatment
 We demonstrated that ADSCs might maintain cardiac function in the DCM hamster model by enhancing ATP concentration, as well as mitochondrial transporter and myosin expression, indicating their potential for DCM treatment
  Platelet-rich plasma PRP therapy is used to treat pathological conditions such as degenerative inflammatory diseases including osteoarthritis OA by enhancing tissue repair and promoting anti-inflammatory effects Although PRP therapy for patients with knee OA improved pain and functional scores, the association of clinical outcomes and quality of PRP including cell composition and concentration is unclear
 
  Therefore, this study analyzed blood cell counts, including the immature platelet fraction IPF, in peripheral blood and PRP of 144 patients with knee OA who underwent PRP therapy The mean leukocyte and platelet concentrations in whole blood and PRP were analyzed using an XN-1000 automated hematology analyzer Visual analogue scale VAS scores and knee injury and osteoarthritis outcome scores KOOS before and 1 month after a single PRP injection were also determined
 
  Higher platelet and lower leukocyte concentration rates were observed in PRP compared with whole blood The platelet concentration in whole blood was negatively correlated with VAS improvement