Obesity often initiates or coexists with certain metabolic abnormalities This study sought to examine the independent and joint relations of weight and metabolic syndrome MetS with incident chronic kidney disease CKD among Chinese elderly people
 
  A total of 15,229 participants mean age 628 years from the Dongfeng-Tongji cohort with complete baseline questionnaire and medical examination data were followed from 2008 to 2010 to 2013 All participants were categorized into four phenotypes metabolically healthy non-overweight/obesity MHNO, metabolically healthy overweight/obesity MHO, metabolically unhealthy non-overweight/obesity MUNO, metabolically unhealthy overweight/obesity MUO Multivariable-adjusted logistic regression models were applied to estimate the odds ratios ORs and confidence intervals CIs of four phenotypes with the risk of incident CKD, which was defined as estimated glomerular filtration rate eGFRlt;60ml/min/173m
   A total of 1151 CKD cases were identified during a mean of 46-year follow-up After adjusting for potential confounders, both overweight/obesity and MetS were associated with higher risk of CKD, and the ORs 95 CI were 132 115-152 and 150 131-173, respectively The risk of CKD was progressively higher in MHO 131, 109-157, MUNO 154, 122-193, and MUO 205, 173-242 as compared with MHNO phenotype, without significant multiplicative interaction between overweight/obesity and MetS P
  =0906 These associations were slightly stronger among those aged gt;60 years or with baseline diabetes
 
  Both overweight/obesity and MetS were associated with an increased risk of CKD It is worth noting that MHO and MUNO also have an elevated risk Maintaining both normal weight and healthy metabolic profile is recommended
 Both overweight/obesity and MetS were associated with an increased risk of CKD It is worth noting that MHO and MUNO also have an elevated risk Maintaining both normal weight and healthy metabolic profile is recommendedOne of the greatest successes of radiotherapy has been its ability to palliate symptoms from advanced and metastatic cancers Unfortunately, patients face barriers to accessing care and the demand for treatment is rising  https//wwwselleckchemcom/products/phi-101html  Rapid access palliative radiotherapy programmes were created in response to these concerns, and over time they have proliferated and succeeded internationally This narrative review provides an overview of programmes that have published their experiences, and discusses how they have improved access to care, increased evidence-based practice, met the needs of vulnerable populations, advanced the roles of multidisciplinary team members, collaborated across medical specialties, educated trainees and referring physicians, and developed new treatment platforms using advanced technologiesPassenger lymphocyte syndrome PLS is caused by the transfer of B-lymphocytes present in the donor graft into the recipient circulation following solid organ or hematopoietic stem cell transplantation These cells may produce antibodies against the recipient's red blood cells, thereby triggering antibody dependent cytotoxicity and erythroid clearance, with potential resulting hemolysis and jaundice Although uncommon, the true incidence is unknown because many cases are subclinical, with only serologic findings or with non significant levels of hemolysis detectable clinically or by laboratory monitoring Thus, these cases may not be detected in the immediate perioperative period No standardized consensus exists on screening for PLS in patients Through a review of the literature from 2009 to 2019, we aim to approximate the incidence of this condition in different solid organ transplant settings, as well as to streamline recognition, detection, and management of PLS early in the disease course to prevent adverse outcomes and minimize invasive therapy The resultant literature review yielded 22 case reports and 8 case series comprising 71 solid organ transplant patients Hematopoietic stem cell transplant cases were excluded, as PLS cases related to solid organ transplant were the primary focus of this review Our institution has traditionally handled PLS on a case-by-case basis, although we hope to improve this process through an introduction of an algorithm based on review of the literature and formalized communication with primary caregivers
  Increased use of ENDS in the US is related to acute adverse events from liquid nicotine exposure This paper provides national estimates of US hospital emergency department visits for exposures from liquid nicotine exposure in individuals aged ≥5 years
 
  In 2018-2019, data from the 2013-2017 National Electronic Injury Surveillance System All Injury Program were used to identify cases of liquid nicotine-related exposures in individuals aged ≥5 years National estimates of exposures related to liquid nicotine exposure in ENDS for those aged ≥5 years by demographic characteristics, symptoms, diagnoses, and treatment dispositions were calculated
 
  From 2013 to 2017, an estimated 2,718 cases related to liquid nicotine among those aged ≥5 years were treated in US hospital emergency departments Most exposures occurred among those who were aged ≥25 years 517, white 741, and male 519 Most case patients were treated and released from the hospitals, and 75 were admitted Poisoning was the most common diagnosis of these exposures 827 The most common symptoms were cardiovascular 297
 
  This study provides national estimates of emergency department visits for injury and poisoning cases related to nicotine exposure from ENDS among individuals aged ≥5 years Although long-term health outcome studies of liquid nicotine exposure are not available, these estimates provide some insight into the acute health effects Findings from this study may inform education programs aimed at preventing exposures related to ENDS products
 This study provides national estimates of emergency department visits for injury and poisoning cases related to nicotine exposure from ENDS among individuals aged ≥5 years Although long-term health outcome studies of liquid nicotine exposure are not available, these estimates provide some insight into the acute health effects Findings from this study may inform education programs aimed at preventing exposures related to ENDS products
  This study examines the demographic characteristics, transgender-specific factors, and discrimination experiences associated with current cigarette smoking, e-cigarette use/vaping, and dual use in a large sample of transgender people
 
  This was a secondary analysis of the 2015 US Transgender Survey n=27,715 Conducted in 2019, logistic regression models were used to estimate the AORs and 95 CIs of current smoking, e-cigarette use/vaping, and dual use among transgender people
 
  Overall, 236 of respondents used cigarettes, 93 used e-cigarettes/vaping products, and 52 reported dual use within the past 30 days Visually nonconforming individuals had greater odds cigarettes AOR=149, 95 CI=135, 165; e-cigarettes/vaping AOR=143, 95 CI=125, 165; dual use AOR=181, 95 CI=152, 215 than visually conforming individuals Transgender people who had disclosed their transgender identity to their social networks had greater odds of cigarette smoking AOR=130, 95 CI=117, 145, e-cigarette use/vasease prevention efforts for transgender populations with increased risks for these health behaviorsIn the head and neck region, preoperative evaluation of the free flap volume is challenging The current study validated preoperative three-dimensional 3D virtual surgical simulation for soft tissue reconstruction by assessing flap volume and evaluated fat and muscle volume changes at follow-up in 13 head and neck cancer patients undergoing anterolateral craniofacial resection Patients received 3D virtual surgical simulation, and the volume of the planned defects was estimated by surgical simulation Following en bloc resection of the tumor, the defect in the skull base was covered using a rectus abdominis myocutaneous flap Following surgery, computed tomography scans were acquired at day 1 and at 6 and 12 months Virtual planned defect was on average 227 ml range, 154-315 and was 10 smaller than the actual flap volume in patients without skin involvement of the tumor Between day 1 and 12 months post-surgery, the volume of fat and muscle tissue in the free flap dropped by 9 and 58, respectively Our results indicate that 3D virtual surgical simulation provides essential information in determining the accurate volume of the required free flap for surgical defect repair and may thus help improve surgical planning and functional and esthetic outcome
  The purpose of this study was to apply a previously reported homologous model for quantifying and visualizing the three-dimensional 3D cranio-mandibular morphology
 
  Twenty-eight 3D cone-beam computed tomography CBCT images of Japanese patients 7 to 13years of age showing skeletal Class 1 malocclusions were used in this study Wire mesh fitting was conducted for each patient based on the assignment of landmarks to each 3D surface homologous modeling Cranial and mandibular images were generated using surface rendering of the CBCT images The mean and standard deviation of each point on the wire mesh were calculated as the normative mean Two operators conducted the process twice for seven patients, with a one-week interval between fittings The intra- and inter-examiner reliability were determined using the 95 confidence interval minimal detectable change MDC
   for random error and intra-class correlation coefficients ICCs
 
  The intra- and inter-examiner reliability of the mesh fitting method were almost perfect Normative ranges of the cranial and mandibular surfaces of Japanese were determined
 
  A clinical method that enables practitioners to quantify and visualize the hard tissues of a patient's face in three dimensions with almost perfect reliability is presented This method allows practitioners to evaluate how patients' skeletal characteristics differ from normative means in three dimensions
 A clinical method that enables practitioners to quantify and visualize the hard tissues of a patient's face in three dimensions with almost perfect reliability is presented This method allows practitioners to evaluate how patients' skeletal characteristics differ from normative means in three dimensions
  The study aimed to investigate the effects of micro-osteoperforations MOPs on the mandibular bone volume/tissue volume BV/TV ratio changes and the rate of orthodontic tooth movement using cone-beam computed tomography images Another objective was to evaluate the effects of MOP frequency intervals 4weeks, 8weeks, and 12weeks on the BV/TV ratio and rate of tooth movement
 
  In 24 participants, 140-200g of force was applied for mandibular canine retraction Three MOPs were made according to the scheduled intervals of the 3 different groups group 1 MOP 4weeks, group 2 MOP 8weeks, and group 3 MOP 12weeks directly at the mandibular buccal cortical bone of extracted first premolars sites Cone-beam computed tomography scans were obtained at the 12th week after MOP application Computed tomography Analyzer software version 11100; Skyscan, Kontich, Belgium was used to compute the trabecular alveolar BV/TV ratio
 
  A significant difference was observed in the rate of canine movement between control and MOP