No hemothorax was recorded Postoperative chylothorax incidence was slightly higher in Group A 25 vs 0; p-value = 021 Total pleural effusion volume at 48 h was significantly higher in Group B 400 285-500 vs 255 150-459 ml p-value = 0005 Chest tube duration was similar in the two groups 5 3-9 vs 5 3-8 days p-value = 077 At multivariable analysis the energy device used was not associated with increased pleural effusion volume p-value = 043 nor with prolonged chest tube duration p-value = 028 Monopolar electrocautery and Harmonic ACE Plus® were safe and had a similar impact on short-term outcomes after VATS lobectomy and lymphadenectomy, suggesting that energy devices choice could be left to surgeon's preference Monopolar electrocautery and Harmonic ACE Plus® were safe and had a similar impact on short-term outcomes after VATS lobectomy and lymphadenectomy, suggesting that energy devices choice could be left to surgeon's preference Good adherence to antiretroviral therapy ART and retention in care are essential for the effectiveness of an HIV care program With the currentincrease in numbers of people living with HIV taking second-line ART in sub-Saharan Africa, there is a need to establish their treatment outcomes and the rate of loss to follow up In this study, we determined the incidence and predictors of loss to follow up among patients taking second-line ART at an experienced HIV treatment center in southwestern Uganda This was a retrospective review of an electronic database at Mbarara Regional Referral Hospital HIV clinic in southwestern Uganda Second-line ART included at least two of the nucleoside reverse transcriptase inhibitors and a boosted protease inhibitor Loss to follow-up was defined as failure to return to the health facility for care or treatment refill for 180days or more from the previous visit After excluding children less than 15years, we pooled data that included socio-demographic, clinical, and laboraiaryHIV center in southwestern Uganda There is a need to routinely measure hemoglobin during clinic reviews, and establish mechanisms to retain males initiated on second-lineART in care The association of anemia and loss to follow up needs to be investigated There is a high incidence of loss to follow up among patients taking protease-inhibitor based second-line ART at a tertiary HIV center in southwestern Uganda There is a need to routinely measure hemoglobin during clinic reviews, and establish mechanisms to retain males initiated on second-line ART in care The association of anemia and loss to follow up needs to be investigated A primary task of the Norwegian helicopter emergency medical services HEMS is to provide advanced medical care to the critical ill and injured outside of hospitals Where HEMS bases are located, directly influences who in the population can be reached within a given response time threshold and who cannot When studying the locations of bases, the focus is often on efficiency, that is, maximizing the total number of people that can be reached within a given set time This approach is known to benefit people living in densely populated areas, such as cities, over people living in remote areas The most efficient solution is thus typically not necessarily a fair one This study aims to incorporate fairness in finding optimal air ambulance base locations We solve multiple advanced mathematical optimization models to determine optimal helicopter base locations, with different optimization criteria related to the level of aversion to inequality, including the utilitarian, Bernoulli-Nash and iso-elastic sociao give full coverage of the country As results differ depending on the mathematical objective, the work shows the importance of not only looking for optimal solutions, but also raising the essential question of 'optimal with respect to what' Generic preference-based measures GPBMs are health-related quality of life HRQoL measures commonly used to evaluate the cost-utility of interventions in healthcare However, the degree to which the content of GPBMs reflect the HRQoL of individuals with chronic obstructive pulmonary disease COPD has not yet been assessed The purpose of this study was to examine the content and convergent validity of GPBMs in people with COPD COPD patients were recruited from healthcare centers in Ontario, Canada The Patient-Generated Index PGI an individualized HRQoL measure and the RAND-36 to obtain SF-6D scores; a GPBM were administered Life areas nominated with the PGI were coded using the International Classification of Functioning Disability and Health and mapped onto GPBMs We included 60 participants with a mean age of 70 and FEV1 predicted of 43 The mean PGI score was 3455/100 and the top three overarching areas that emerged were 'mobility' 2593, 'recreation and leisure' 2519 and 'domestic life' 1926 Mapping of the nominated areas revealed that the Quality of Well-Being scale covered the highest number of areas 8462, Health Utilities Indices covered the least 1538 and 3077 and other GPBMs covered between 46 and 62 A correlation of 032 was calculated between the SF-6D and the PGI The majority of GPBMs covered approximately half of the areas reported as being important to individuals with COPD When areas relevant to COPD are not captured, HRQoL scores generated by these measures may inaccurately reflect patients' values and affect cost-effectiveness decisions The majority of GPBMs covered approximately half of the areas reported as being important to individuals with COPD When areas relevant to COPD are not captured, HRQoL scores generated by these measures may inaccurately reflect patients' values and affect cost-effectiveness decisions DNA vaccine is one of the research hotspots in veterinary vaccine development Several advantages, such as cost-effectiveness, ease of design and production, good biocompatibility of plasmid DNA, attractive biosafety, and DNA stability, are found in DNA vaccines In this study, the plasmids expressing bovine herpesvirus 1 BoHV-1 gB, gC, and gD proteins were mixed at the same mass ratio and adsorbed polyethyleneimine PEI magnetic beads with a diameter of 50nm Further, the plasmid and PEI magnetic bead polymers were packaged into double carboxyl polyethylene glycol PEG 600 to use as a DNA vaccine The prepared DNA vaccine was employed to vaccinate mice via the intranasal route The immune responses were evaluated in mice after vaccination The expression of viral proteins could be largely detected in the lung and rarely in the spleen of mice subjected to a vaccination The examination of biochemical indicators, anal temperature, and histology indicated that the DNA vaccine was safe in vivo Howeverf plasmids expressing BoHV-1 gB/gC/gD proteins by nano-carrier through intranasal route could effectively activate long-term humoral, cellular, and mucosal immune responses at high levels in mice These data indicate PEI magnetic beads combining with PEG600 are an efficient vector for plasmid DNA to deliver intranasally as a DNA vaccine candidate Mitral regurgitation is a frequent valvular disease, with an increasing prevalence We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types A single-centre, retrospective analysis of mitral valve surgeries conducted between January 2005 and December 2015 for patients undergoing first-line mitral valve repair with either open Cosgrove or closed CE Physio / Physio II annuloplasty OA or CA, respectively rings In total, 1120 patient documentations were available of which 528 underwent OA and 592 patients CA The median age of patients was 640 years and 411 were female The majority of these patients underwent the procedure because of degenerative valve disease Rates of successful repair were about 90, 72 h procedural mortality was 06 and the rate of re-intervention was 06 within the first 30 days Functional mitral regurgitation, left ventricular ejection fraction, left ventricular end-diastolic and systolic diameter and New York Heart Association class as well as hard outcomes were comparable 777 and 744 of patients were alive at the 10-year follow-up in the OA and CA groups, respectively https//wwwselleckchemcom/products/AZD0530html Upon multivariable adjustment, the hazard ratio was 0926 95 CI 0642-13135; p = 0681 The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations Capgras delusion is one of the delusional misidentification syndromes characterized by the belief by the patient that the close person is replaced by an imposter who looks physically the same It rarely occurs in Postpartum Psychosis An intriguing phenomenon with ongoing debates, particularly about its feature and prevalence, its course, occurrence, and phenomenon in the postpartum period are poorly understood A 26-year-old Nepalese woman presented to the emergency for abnormal behavior on her 9th postpartum day Capgras delusion was observed for 2days during her hospital stay Other psychotic symptoms appeared progressively and were treated as a case of Postpartum Psychosis This case describes the temporal sequence of various psychopathologies during Postpartum Psychosis including Capgras delusion We attempt to explain the occurrence of Capgras delusion in Postpartum Psychosis This case describes the temporal sequence of various psychopathologies during Postpartum Psychosis including Capgras delusion We attempt to explain the occurrence of Capgras delusion in Postpartum Psychosis The aim of this systematic review was to summarize and assess the literature on quality of life QoL among cancer patients 80years and older admitted to hospitals and what QoL instruments have been used We searched systematically in Medline, Embase and Cinahl Eligibility criteria included studies with any design measuring QoL among cancer patients 80years and older hospitalized for treatment surgery, chemotherapy or radiation therapy studies not available in English, French, German or Spanish We screened the titles and abstracts according to a predefined set of inclusion criteria All the included studies were assessed according to the Critical Appraisal Skills Programme checklists, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement checklist was used to ensure rigor in conducting and reporting This systematic review was registered in PROSPERO CRD42017058290 We included 17 studies with 2005 participants with various cancer diagnoses and Classification of Malignant Tumors stages TNM